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Cyclic MKEY

CAS No. 934385-55-4

Cyclic MKEY( —— )

Catalog No. M30319 CAS No. 934385-55-4

MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cyclic MKEY
  • Note
    Research use only, not for human use.
  • Brief Description
    MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.
  • Description
    MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CXCL4-CCL5 heterodimer formation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    934385-55-4
  • Formula Weight
    2532.89
  • Molecular Formula
    C113H174N28O34S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Cys}{Lys}{Glu}{Tyr}{Phe}{Tyr}{Thr}{Ser}{Ser}{Lys}{Ser}{Ser}{Asn}{Leu}{Ala}{Val}{Val}{Phe}{Val}{Thr]

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615.
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